The veterinary mRNA vaccine platform project of Huiliao Bio was evaluated as a key scientific and technological research and development plan in Jiangsu Province in 2023.

On October 9, 2023, the Jiangsu Provincial Department of Science and Technology released the list of proposed projects for the 2023 Jiangsu Provincial Science and Technology Plan Special Fund (Key R&D Plan for Modern Agriculture) and the Carbon Peak and Carbon Neutrality Science and Technology Innovation Special Fund (Key Technology Research in the Field of Agriculture and Rural Areas). The project titled "Innovation in Key Technologies and Development of a Trivalent mRNA Vaccine for Porcine Rotavirus," developed by HuiLiao Bio's veterinary mRNA vaccine platform, was successfully approved.

This project aims to design a trivalent mRNA vaccine (targeting G9, G5, and G4) for porcine rotavirus (PoRV) using the major protective antigen (VP7) as the target and the CLS delivery system. The study will investigate the immunological properties of the vaccine and evaluate its efficacy in preventing porcine rotavirus-induced diarrhea through immunization and challenge protection trials in pigs. The results will provide a theoretical foundation and data support for the development of a novel PoRV vaccine. This initiative not only contributes to safeguarding the healthy development of China's pig farming industry but also helps block the transmission route of porcine rotavirus to humans, holding significant public health implications.